Category Archives: Research

Research

Paper: porous media

T Jacobs, GO Lloyd, J-A Gertenbach, KK Müller-Nedebock, C Esterhuysen, and L Barbour “In situ X-ray Structural Studies of a Flexible Host Responding to Incremental Gas Loading” Angew. Chem. Int. Ed. 51, 4913–4916 (2012).

Polymers and filaments in confined geometries

Imagine the filaments forming the cytoskeleton of a cell.  They are confined within the cell membrane.  Not only do these filaments influence how the cell might  behave mechanically, but how the filaments behave is coupled to the restricted space in which they grow, arrange or combine into networks.  Similarly one can think of polymers inside… Read More »

Paper: Molecular dynamics simulations of polymer systems under geometrical confinement

Arash Azari, Kristian K. Müller-Nedebock “Entropic competition in polymeric systems under geometrical confinement”, EPL 110 68004 doi:10.1209/0295-5075/110/68004 (alternatively, http://arxiv.org/abs/1408.5312) We present simulations of alternating copolymers of segments of different stiffness that are confined within regions.  Mixtures of different chains then have different arrangements depending on the size of the confining region. In another paper we shall be… Read More »

Active systems

Molecular machines are responsible for a variety of non-equilibrium actions. They can make cells themselves move about, and perhaps exhibit fascinating collective motion, and the are responsible, amongst other things, for the transportation of cargo, or play a role in the tightening of the contractile ring during cells division. A range of molecular motors move… Read More »

Collaborator: Ben Loos

Dr Ben Loos (Dept of Physiological Sciences at Stellenbosch University) has a long-standing interest in the molecular mechanisms that control cell death susceptibility. His research centres around protein degradative mechanisms and their dynamics, transport and function of mitochondria along tubulin networks and their role in neuronal degeneration and migration.  His research group utilizes in vitro… Read More »